Team#1 (German Coordinator)
Professor Siegfried Labeit
Department of Integrative Pathophysiology (Head)
Medical Faculty Mannheim, University of Heidelberg,
Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, GERMANY
Email: Labeit@embl.de
Team#2 (North American Coordinator)
Professor Henk L. Granzier
Department of Physiology, University of Arizona
Medical Research Building 340, 1656 East Mabel Street
Tucson, AZ 85724-5217, U.S.A.
Email: Granzier@email.arizona.edu
Team#3
Professor Ralph Knoell
ICMC (Integrated Cardio Metabolic Centre)
Karolinska Institutet
Karolinska University Hospital in Huddinge (M54)
SE 141 86 Stockholm, Sweden
Email:ralph.knoell@ki.se
Team#4
Dr. Olga Mayans
School of Biological Sciences
Biosciences Building (BSB) Crown Street
University of Liverpool, Liverpool L69 7ZB, U.K.
Email: Olga.Mayans@liv.ac.uk
Team #5
Isabelle Richard, Ph.D.
Généthol-CNRS UMR8115,1 rue de l'internationale,
91000 Evry, FRANCE,
Email: Richard@igenethon.fr
Team#6
Ju Cher, Ph.D.
Professor of Medicine
(co-PI:Stephan Lange, Ph.D.)
AHA Endowed Char, Director of Basic Cardiac Research
UCSD School of medicine
9500 Gilman Drive, La Jolla
CA 92093-0613C U.S.A.
juchen@ucsd.edu
Team #7
H.Lee Sweeney, Ph.D.
Department of Physiology
University Pennsylvania School of Medicine
37th and Hamilton Walk,
Philadelphia, PA 19104-6085 U.S.A.
lsweeney@mail.med.upenn.edu
Collaborator #1
Michael Gotthardt, M.D.
Max-Delbrück Zentrum für Molekulare Medizin, Berlin –Buch Role:
Titin stiffness modulation by splicing and provision of spring element KO mice.
Collaborator #2
Michael Gramlich, M.D.
University Hospital Tübingen, Germany Role:
Rescue by exon skipping and provision of titin FS-exon 326 mouse model.
Collaborator #3
Prof. Robin Leatherbarrow
Dept of Chemical Biology, Faculty of Natural Sciences, South Kensington Campus, Imperial College, London, UK Role:
Synthesis of telethonin/TCAP inhibitors
Collaborator #4
Martin LeWinter, MD
Chief of Cardiology University of Vermont Burlington, VT 05405-0160 Role:
Collaborator on mechanoptosis in HF with titin-based diastolic stiffening
Collaborator #5
Professor Coen Ottenheijm
VU University Medical Center University of Amsterdam
Laboratory for Physiology, Institute for Cardiovascular Research
Van der Boechorststraat 7
1081 BT, Amsterdam. NETHERLANDS
Email: c.ottenheijm@vumc.nl
Collaborator #6
Dilson Rassier , M.D.
McGill University, Department of Physiology 475 avenue des Pins Ouest Montreal Quebec Canada Role:
Stress sensing at the level of single sarcomeres
